Boost Your Bio Skills with the SACE Stage 2 Biology Exam 2026 – Dive into Biology Brilliance!

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During which phase do sister chromatids remain attached at the centromere?

Telophase I

Anaphase I

Sister chromatids remain attached at the centromere during Anaphase I of meiosis. At this phase, homologous chromosomes are separated, while the sister chromatids of each chromosome remain connected at their centromeres. This is a key difference between meiosis and mitosis, where sister chromatids are separated during anaphase.

During Anaphase I, the focus is on the separation of the homologous chromosomes, which move towards opposite poles of the cell, leaving the sister chromatids intact. This preserves the genetic information until the next round of division, where the sister chromatids will eventually be separated during Anaphase II. Other phases mentioned do not correspond to this condition; for instance:

- In Telophase I, homologous chromosomes have already separated, and the cell is preparing to divide.

- In Prophase II, the sister chromatids are still paired but this is after the separation of homologous chromosomes has already occurred in the first meiotic division.

- In Metaphase II, sister chromatids align at the cell equator and are prepared to be pulled apart, indicating that they should not still be attached at that stage.

Thus, the correct identification of Anaphase I as the phase where sister

Prophase II

Metaphase II

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